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CS-W001157 4
Total: USD 88.00

4-(Morpholino)phenylboronic acid

  • CAS No. 186498-02-2

  • Cat. No. CS-W009091
  • Purity≥97%
  • MDL No.MFCD03095169

*For research and further manufacturing use only, not for direct human use.

4-(Morpholino)phenylboronic acid|CS-W009091

Structure of 186498-02-2

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General Information

  • CAS No. 186498-02-2
  • Cat. No. CS-W009091
  • Purity ≥97%
  • MDL No. MFCD03095169
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄BNO₃
  • Molecular Weight 207.04
  • Synonym(s) 4-Morpholinophenylboronic acid
  • SMILES OB(C1=CC=C(N2CCOCC2)C=C1)O

Application

4-(Morpholino)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The morpholino group enhances solubility and modulates electronic properties, while the boronic acid functionality offers excellent stability, ease of handling, and compatibility with diverse functional groups. Its utility spans pharmaceutical intermediate synthesis and materials chemistry, particularly in the development of conjugated systems and heterocyclic architectures.

Synthesis

  • Route1

    References

    • US2004/14755 A1, ; Page/Page column 77 ; US 20040014755 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.93
  • LogP   -0.797
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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