Lot numbers can be found on the outside label of a product:
2,4-Dichlorothieno[3,2-d]pyrimidine
-
CAS No. 16234-14-3
- Cat. No. CS-B0058
- Purity≥96%
- MDL No.MFCD08448158
*For research and further manufacturing use only, not for direct human use.
![2,4-Dichlorothieno[3,2-d]pyrimidine|CS-B0058](https://file.chemscene.com/productPIC/CS-B0058.gif)
Structure of 16234-14-3
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 16234-14-3
- Cat. No. CS-B0058
- Purity ≥96%
- MDL No. MFCD08448158
- Storage -20°C, sealed storage, away from moisture
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₂Cl₂N₂S
- Molecular Weight 205.06
- Synonym(s) None
- SMILES ClC=1N=C(Cl)C=2SC=CC2N1
Description
2,4-Dichlorothieno[3,2-d]pyrimidine features a fused thienopyrimidine core with strategically positioned chlorine atoms enhancing electrophilic reactivity. This electron-deficient heterocycle serves as a key scaffold in kinase inhibitor design and medicinal chemistry campaigns. The molecule exhibits robust stability under standard bench conditions and integrates readily into modular synthesis workflows.
Application
2,4-Dichlorothieno[3,2-d]pyrimidine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of purine-like scaffolds. The dichloro substitution pattern facilitates regioselective cross-coupling and nucleophilic displacement reactions, while the thienopyrimidine core offers enhanced metabolic stability and favorable binding interactions. Bench-stable and amenable to purification via flash chromatography, it functions effectively in the synthesis of kinase inhibitors and other bioactive compounds.
Synthesis
-
Route1
-
In-stock
![Thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione|CS-B0057](https://file.chemscene.com/productPIC/CS-B0057.gif)
16233-51-5 - ~99%
-
In-stock
16234-14-3
References
-
Verheijen, Jeroen C.; Yu, Ker; Toral-Barza, Lourdes; Hollander, Irwin; Zask, Arie Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 1 p. 375 - 379
-
-
Route2
-
In-stock
22288-78-4 - ~%
-
In-stock
16234-14-3
References
-
WO2011/130628 A1, ; WO 2011/130628 A1
-
-
References
-
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 8 p. 2408 - 2411
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 25.78
- LogP 2.9981
- H_Acceptors 3
- H_Donors 0
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2,4-Dichlorothieno[3,2-d]pyrimidine sigma2,4-Dichlorothieno[3,2-d]pyrimidine manufacturer2,4-Dichlorothieno[3,2-d]pyrimidine price2,4-Dichlorothieno[3,2-d]pyrimidine structure2,4-Dichlorothieno[3,2-d]pyrimidine SDSbuy 2,4-Dichlorothieno[3,2-d]pyrimidine2,4-Dichlorothieno[3,2-d]pyrimidine supplier2,4-Dichlorothieno[3,2-d]pyrimidine uses2,4-Dichlorothieno[3,2-d]pyrimidine molecular weightprice of 2,4-Dichlorothieno[3,2-d]pyrimidine2,4-Dichlorothieno[3,2-d]pyrimidine chemical name formula of 2,4-Dichlorothieno[3,2-d]pyrimidine