Lot numbers can be found on the outside label of a product:
tert-Butyl 4-(4-hydroxybutyl)piperidine-1-carboxylate
-
CAS No. 142355-83-7
- Cat. No. CS-D1088
- Purity≥95%
- MDL No.MFCD03265708
*For research and further manufacturing use only, not for direct human use.
Structure of 142355-83-7
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 142355-83-7
- Cat. No. CS-D1088
- Purity ≥95%
- MDL No. MFCD03265708
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₄H₂₇NO₃
- Molecular Weight 257.37
- Synonym(s) None
- SMILES O=C(OC(C)(C)C)N1CCC(CC1)CCCCO
Description
tert-Butyl 4-(4-hydroxybutyl)piperidine-1-carboxylate features a piperidine core functionalized with a hydroxyalkyl side chain, enabling downstream derivatization in medicinal chemistry. The tert-butyl ester group provides stability and ease of removal under mild acidic conditions, facilitating incorporation into complex molecular architectures. This compound serves as a key intermediate for bioactive molecule synthesis.
Application
tert-Butyl 4-(4-hydroxybutyl)piperidine-1-carboxylate serves as a versatile bifunctional building block for medicinal chemistry and process synthesis. The piperidine core provides a pharmacophoric scaffold, while the pendant hydroxyl group enables facile derivatization via esterification, etherification, or oxidation to aldehyde/ketone. The tert-butyl carbamate offers excellent stability and orthogonality in multi-step syntheses, facilitating selective deprotection under mild acidic conditions. Its compatibility with standard coupling and protection protocols makes it ideal for constructing complex heterocyclic systems and API intermediates.
Synthesis
-
Route1
-
In-stock
142247-38-9 - ~98%
-
In-stock
142355-83-7
References
-
Egbertson, Melissa S.; Chang, Charles T.-C.; Duggan, Mark E.; Gould, Robert J.; Halczenko, Wasyl; et al. Journal of Medicinal Chemistry, 1994 , vol. 37, # 16 p. 2537 - 2551
-
-
Route2
-
199475-41-7 -
In-stock
24424-99-5 - ~%
-
In-stock
142355-83-7
References
-
US6451816 B1, ;
-
-
Route3
-
403857-14-7 - ~87%
-
In-stock
142355-83-7
References
-
Song, Xiaoping; He, Henry T.; Siahaan, Teruna J. Organic Letters, 2002 , vol. 4, # 4 p. 549 - 552
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 49.77
- LogP 2.7961
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 4
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 142355-83-7 sigma142355-83-7 manufacturer142355-83-7 price142355-83-7 structure142355-83-7 SDSbuy 142355-83-7142355-83-7 supplier142355-83-7 uses142355-83-7 molecular weightprice of 142355-83-7142355-83-7 chemical name formula of 142355-83-7