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CS-W001157 4
Total: USD 88.00

Monomethyl phthalate

  • CAS No. 4376-18-5

  • Cat. No. CS-D1453
  • Purity≥98%
  • MDL No.MFCD00002466

*For research and further manufacturing use only, not for direct human use.

Monomethyl phthalate|CS-D1453

Structure of 4376-18-5

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General Information

  • CAS No. 4376-18-5
  • Cat. No. CS-D1453
  • Purity ≥98%
  • MDL No. MFCD00002466
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈O₄
  • Molecular Weight 180.16
  • Synonym(s) 2-(Methoxycarbonyl)benzoic acid
  • SMILES O=C(C1=CC=CC=C1C(O)=O)OC

Description

.

Application

Monomethyl phthalate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to phthalic acid derivatives and substituted aromatic systems. Its ester functionality exhibits excellent bench stability and compatibility with standard reaction conditions, facilitating transformations such as hydrolysis, nucleophilic substitution, and coupling reactions. The molecule functions effectively in the synthesis of pharmaceutical intermediates and specialty polymers, offering predictable reactivity and straightforward purification.

Synthesis

  • Route1

    References

    • Ager; Prakash Synthetic Communications, 1995 , vol. 25, # 5 p. 739 - 742
  • Route2
    • null|null
      124-38-9
    • In-stock
      Methyl 2-iodobenzoate|CS-W007334
      610-97-9
    • ~79%
    • In-stock
      Monomethyl phthalate|CS-D1453
      4376-18-5

    References

    • Ebert, Greg W.; Juda, Wayne L.; Kosakowski, Robert H.; Ma, Bing; Dong, Liming; Cummings, Keith E.; Phelps, Mwita V. B.; Mostafa, Adel E.; Luo, Jianyuan Journal of Organic Chemistry, 2005 , vol. 70, # 11 p. 4314 - 4317
  • Route3
    • null|null
      73513-53-8
    • ~93%
    • In-stock
      Monomethyl phthalate|CS-D1453
      4376-18-5

    References

    • Sridhar, P. Ramu; Sinha, Surajit; Chandrasekaran Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 1 p. 157 - 160

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.6
  • LogP   1.1714
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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