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CS-W001157 4
Total: USD 88.00

4-(1-Boc-piperidin-4-yl)butanoic acid

  • CAS No. 142247-38-9

  • Cat. No. CS-W003175
  • Purity≥97%
  • MDL No.MFCD04114965

*For research and further manufacturing use only, not for direct human use.

4-(1-Boc-piperidin-4-yl)butanoic acid|CS-W003175

Structure of 142247-38-9

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General Information

  • CAS No. 142247-38-9
  • Cat. No. CS-W003175
  • Purity ≥97%
  • MDL No. MFCD04114965
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₅NO₄
  • Molecular Weight 271.35
  • Synonym(s) 4-[1-(tert-butoxycarbonyl)piperidin-4-yl]butanoic acid
  • SMILES O=C(N1CCC(CC1)CCCC(=O)O)OC(C)(C)C

Description

This 4-(1-Boc-piperidin-4-yl)butanoic acid features a robust Boc-protected piperidine moiety linked via a flexible butanoyl tether, enabling seamless incorporation into peptide conjugates and bioactive molecule scaffolds under standard conditions.

Synthesis

  • Route1
    • null|null
      142355-82-6
    • ~97%
    • In-stock
      4-(1-Boc-piperidin-4-yl)butanoic acid|CS-W003175
      142247-38-9

    References

    • Egbertson, Melissa S.; Chang, Charles T.-C.; Duggan, Mark E.; Gould, Robert J.; Halczenko, Wasyl; et al. Journal of Medicinal Chemistry, 1994 , vol. 37, # 16 p. 2537 - 2551
  • Route2
    • (E)-Ethyl 4-(diethoxyphosphoryl)but-2-enoate|CS-0356393
      42516-28-9
    • null|null
      79099-07-3
    • ~99%
    • In-stock
      4-(1-Boc-piperidin-4-yl)butanoic acid|CS-W003175
      142247-38-9

    References

    • Merck and Co., Inc. Patent: US6399619 B1, 2002 ; US 6399619 B1
  • Route3
    • tert-Butyl 4-(4-ethoxy-4-oxobutyl)piperidine-1-carboxylate|CS-0737229
      142247-37-8
    • ~%
    • In-stock
      4-(1-Boc-piperidin-4-yl)butanoic acid|CS-W003175
      142247-38-9

    References

    • US5264420 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   2.8884
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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