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Structure of 1392234-97-7
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This boronate ester features a 2-fluoro-5-hydroxyphenyl scaffold, enabling direct coupling in Suzuki-Miyaura reactions. The tetramethyl-1,3,2-dioxaborolane moiety imparts exceptional stability and moisture tolerance, simplifying handling under standard conditions.
2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. Its stability under ambient conditions and compatibility with diverse functional groups enable reliable C–C bond formation. The ortho-fluoro substituent enhances reactivity in palladium-catalyzed couplings, facilitating the synthesis of substituted biaryls and heterocyclic scaffolds common in medicinal chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: