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Structure of 913835-74-2
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This boronic acid features a fluorinated phenyl ring with a strategically positioned hydroxyl group, enhancing solubility and reactivity in Suzuki-Miyaura coupling reactions. The electron-withdrawing fluorine substituent improves stability and directs regioselective functionalization.
(4-Fluoro-3-hydroxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation with aryl and vinyl halides. Its hydroxyl group provides enhanced solubility and facilitates downstream derivatization, while the fluorine substituent offers metabolic stability and modulates electronic properties. The boronic acid moiety exhibits excellent bench stability and compatibility with diverse reaction conditions, making it a reliable reagent for constructing complex phenolic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: