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CS-W001157 4
Total: USD 88.00

2-Fluoro-3-hydroxyphenylboronic acid

  • CAS No. 855230-60-3

  • Cat. No. CS-B1249
  • Purity≥95%
  • MDL No.MFCD06797222
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-3-hydroxyphenylboronic acid|CS-B1249

Structure of 855230-60-3

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Description

2-Fluoro-3-hydroxyphenylboronic acid features a boronate moiety ortho to a hydroxyl group and fluoro substitution, enabling selective coupling in Suzuki-Miyaura reactions. This configuration enhances reactivity while maintaining bench-stable handling under standard conditions.

Application

2-Fluoro-3-hydroxyphenylboronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The ortho-fluoro and hydroxyl groups provide enhanced regioselectivity and functional group tolerance, while the boronic acid moiety offers good bench stability and ease of purification. This compound facilitates access to fluorinated aromatic systems relevant in medicinal chemistry and materials science.

General Information

  • CAS No. 855230-60-3
  • Cat. No. CS-B1249
  • Purity ≥95%
  • MDL No. MFCD06797222
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆BFO₃
  • Molecular Weight 155.92
  • Synonym(s) Boronic acid,(2-fluoro-3-hydroxyphenyl)-; (2-Fluoro-3-hydroxyphenyl)boronic acid
  • SMILES OC1=C(F)C(B(O)O)=CC=C1

Computational Chemistry Data

  • TPSA   60.69
  • LogP   -0.7889
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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