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Structure of 760990-08-7
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2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol features a boronate ester group flanked by a fluorinated aryl moiety, enabling efficient Suzuki-Miyaura coupling under standard conditions. This bench-stable reagent integrates readily into complex molecular architectures, offering precise control over regioselective C–C bond formation in synthetic and medicinal chemistry workflows.
2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The phenolic hydroxyl group enables direct functionalization or derivatization, while the pinacol borane moiety provides excellent stability, ease of handling, and compatibility with a broad range of reaction conditions. This reagent facilitates efficient C–C bond formation in the synthesis of biaryl scaffolds, particularly valuable in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: