Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(4-Fluoro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

  • CAS No. 425378-85-4

  • Cat. No. CS-0101259
  • Purity≥97%
  • MDL No.MFCD11227055

*For research and further manufacturing use only, not for direct human use.

2-(4-Fluoro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0101259

Structure of 425378-85-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 425378-85-4
  • Cat. No. CS-0101259
  • Purity ≥97%
  • MDL No. MFCD11227055
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈BFO₃
  • Molecular Weight 252.09
  • Synonym(s) 4-Fluoro-3-methoxyphenylboronic acid pinacol ester
  • SMILES CC1(C)C(C)(C)OB(C2=CC=C(F)C(OC)=C2)O1

Description

This boronate ester features a 4-fluoro-3-methoxyphenyl group coupled to a tetramethyl-1,3,2-dioxaborolane scaffold. It offers enhanced stability and reactivity in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The electron-withdrawing fluorine and methoxy substituents fine-tune reactivity while maintaining excellent bench-stability and moisture tolerance.

Application

2-(4-Fluoro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its ortho-fluoro and meta-methoxy substituents provide predictable regioselectivity and enhanced functional group tolerance. The tetramethyl-substituted dioxaborolane ring ensures excellent shelf stability and compatibility with aqueous workups, enabling efficient coupling with aryl halides and triflates in diverse synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   27.69
  • LogP   2.1335
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 425378-85-4 sigma425378-85-4 manufacturer425378-85-4 price425378-85-4 structure425378-85-4 SDSbuy 425378-85-4425378-85-4 supplier425378-85-4 uses425378-85-4 molecular weightprice of 425378-85-4425378-85-4 chemical name formula of 425378-85-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label