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CS-W001157 4
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trans-3-(Benzyloxy)cyclobutanol

  • CAS No. 1383813-54-4

  • Cat. No. CS-0047819
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

trans-3-(Benzyloxy)cyclobutanol|CS-0047819

Structure of 1383813-54-4

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General Information

  • CAS No. 1383813-54-4
  • Cat. No. CS-0047819
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄O₂
  • Molecular Weight 178.23
  • Synonym(s) (1R,3r)-3-(benzyloxy)cyclobutanol
  • SMILES O[C@H]1C[C@@H](C1)OCC1=CC=CC=C1

Description

trans-3-(Benzyloxy)cyclobutanol features a rigid cyclobutane core with a benzyloxy group positioned trans to the hydroxyl, enabling precise stereochemical control in synthetic applications. This bench-stable scaffold integrates readily into complex molecular architectures, offering predictable reactivity and enhanced solubility in organic media.

Application

trans-3-(Benzyloxy)cyclobutanol serves as a valuable chiral building block in synthetic organic chemistry, offering predictable stereochemical control due to its rigid cyclobutane framework. The benzyloxy group provides orthogonal protection for hydroxyl functionalities, enabling selective transformations under standard conditions. Its bench-stable nature and compatibility with common coupling and reduction protocols make it well-suited for iterative synthesis of complex cyclic architectures and pharmaceutical intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   1.7265
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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