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cis-3-(Benzyloxy)cyclobutan-1-ol

  • CAS No. 233276-35-2

  • Cat. No. CS-0017753
  • Purity≥95%
  • MDL No.MFCD18633183

*For research and further manufacturing use only, not for direct human use.

cis-3-(Benzyloxy)cyclobutan-1-ol|CS-0017753

Structure of 233276-35-2

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General Information

  • CAS No. 233276-35-2
  • Cat. No. CS-0017753
  • Purity ≥95%
  • MDL No. MFCD18633183
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄O₂
  • Molecular Weight 178.23
  • Synonym(s) cis-3-(Benzyloxy)cyclobutan-1-ol; (1s,3s)-3-(benzyloxy)cyclobutan-1-ol
  • SMILES O[C@@H]1C[C@H](OCC2=CC=CC=C2)C1

Description

cis-3-(Benzyloxy)cyclobutan-1-ol features a rigid cyclobutane scaffold with stereochemically defined hydroxyl and benzyloxy groups, enabling precise spatial positioning in synthetic intermediates. This bench-stable derivative integrates readily into complex molecular architectures requiring controlled polarity and conformational restraint.

Application

cis-3-(Benzyloxy)cyclobutan-1-ol serves as a versatile chiral building block in synthetic organic chemistry, offering a rigid cyclobutane scaffold with orthogonal functional groups. The benzyloxy group provides stable protection for the adjacent hydroxyl, enabling selective transformations. Its stereochemistry facilitates controlled reactivity in ring-opening and coupling reactions, while the bench-stable nature supports straightforward handling and purification in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   1.7265
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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