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CS-W001157 4
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3-Methoxycyclobutan-1-ol

  • CAS No. 1432680-25-5

  • Cat. No. CS-0056983
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Methoxycyclobutan-1-ol|CS-0056983

Structure of 1432680-25-5

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General Information

  • CAS No. 1432680-25-5
  • Cat. No. CS-0056983
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀O₂
  • Molecular Weight 102.13
  • Synonym(s) 3-Methoxycyclobutanol
  • SMILES OC1CC(OC)C1

Description

3-Methoxycyclobutan-1-ol features a cyclobutane ring with strategically positioned hydroxyl and methoxy groups, offering enhanced solubility and stability. This scaffold integrates readily into synthetic sequences requiring polar, rigid motifs under standard conditions.

Application

3-Methoxycyclobutan-1-ol serves as a versatile synthetic intermediate featuring a cyclobutanone-derived scaffold with orthogonal functional handles. The hydroxyl group enables derivatization via esterification or etherification, while the methoxy substituent provides steric and electronic modulation. Its constrained ring system facilitates incorporation into bioactive heterocycles and serves as a building block in medicinal chemistry campaigns requiring rigid, polar motifs. Bench-stable and amenable to standard purification methods, it functions reliably in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   0.1561
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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