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CS-W001157 4
Total: USD 88.00

Cyclobutanecarboxamide

  • CAS No. 1503-98-6

  • Cat. No. CS-D0904
  • Purity≥97%
  • MDL No.MFCD00029076

*For research and further manufacturing use only, not for direct human use.

Cyclobutanecarboxamide|CS-D0904

Structure of 1503-98-6

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General Information

  • CAS No. 1503-98-6
  • Cat. No. CS-D0904
  • Purity ≥97%
  • MDL No. MFCD00029076
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉NO
  • Molecular Weight 99.13
  • Synonym(s) None
  • SMILES O=C(C1CCC1)N

Description

Cyclobutanecarboxamide features a strained four-membered ring that imparts unique conformational rigidity, enhancing its utility in medicinal chemistry. This bench-stable amide integrates readily into bioactive scaffolds, where its compact structure influences target binding and metabolic stability.

Application

Cyclobutanecarboxamide serves as a valuable building block in medicinal chemistry, offering a rigid, strained cyclobutane scaffold that enhances metabolic stability and bioavailability. Its amide functionality enables diverse transformations, including reductive cleavage, N-alkylation, and coupling reactions, while maintaining bench stability and compatibility with common protecting group strategies.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.09
  • LogP   0.2718
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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