Lot numbers can be found on the outside label of a product:
Ethyl 4,6-dichloro-5-fluoronicotinate
-
CAS No. 154012-17-6
- Cat. No. CS-0151707
- Purity≥97%
- MDL No.MFCD18256592
*For research and further manufacturing use only, not for direct human use.
Structure of 154012-17-6
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 154012-17-6
- Cat. No. CS-0151707
- Purity ≥97%
- MDL No. MFCD18256592
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₆Cl₂FNO₂
- Molecular Weight 238.04
- Synonym(s) Ethyl 4,6-dichloro-5-fluoropyridine-3-carboxylate, 2,4-Dichloro-5-(ethoxycarbonyl)-3-fluoropyridine
- SMILES CCOC(=O)C1=CN=C(C(=C1Cl)F)Cl
Description
Ethyl 4,6-dichloro-5-fluoronicotinate is a bench-stable, electron-deficient heterocyclic ester featuring orthogonal halogen handles. This trifunctional scaffold enables direct coupling in cross-coupling and C–H functionalization reactions, delivering access to fluorinated pyridine derivatives under standard conditions.
Application
Ethyl 4,6-dichloro-5-fluoronicotinate serves as a versatile building block in heterocyclic synthesis, enabling the construction of fluorinated pyridine scaffolds relevant to medicinal chemistry. Its dual chloro substituents at C4 and C6 facilitate selective cross-coupling reactions, while the electron-withdrawing fluoro group enhances reactivity in nucleophilic substitution processes. The ester functionality provides a handle for downstream transformations, offering excellent bench stability and compatibility with standard purification methods.
Synthesis
-
Route1
-
6317-97-1 - ~%
-
In-stock
154012-17-6
References
-
Sanchez; Gogliotti Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 4 p. 855 - 859
-
-
Route2
-
In-stock
154012-15-4 - ~%
-
In-stock
154012-17-6
References
-
Sanchez; Gogliotti Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 4 p. 855 - 859
-
-
Route3
-
In-stock
154012-16-5 - ~%
-
In-stock
154012-17-6
References
-
Sanchez; Gogliotti Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 4 p. 855 - 859
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 39.19
- LogP 2.7042
- H_Acceptors 3
- H_Donors 0
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Ethyl 4,6-dichloro-5-fluoronicotinate sigmaEthyl 4,6-dichloro-5-fluoronicotinate manufacturerEthyl 4,6-dichloro-5-fluoronicotinate priceEthyl 4,6-dichloro-5-fluoronicotinate structureEthyl 4,6-dichloro-5-fluoronicotinate SDSbuy Ethyl 4,6-dichloro-5-fluoronicotinateEthyl 4,6-dichloro-5-fluoronicotinate supplierEthyl 4,6-dichloro-5-fluoronicotinate usesEthyl 4,6-dichloro-5-fluoronicotinate molecular weightprice of Ethyl 4,6-dichloro-5-fluoronicotinateEthyl 4,6-dichloro-5-fluoronicotinate chemical name formula of Ethyl 4,6-dichloro-5-fluoronicotinate