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CS-W001157 4
Total: USD 88.00

4,6-Dichloropicolinaldehyde

  • CAS No. 132683-62-6

  • Cat. No. CS-0145986
  • Purity≥97%
  • MDL No.MFCD10698614

*For research and further manufacturing use only, not for direct human use.

4,6-Dichloropicolinaldehyde|CS-0145986

Structure of 132683-62-6

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General Information

  • CAS No. 132683-62-6
  • Cat. No. CS-0145986
  • Purity ≥97%
  • MDL No. MFCD10698614
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃Cl₂NO
  • Molecular Weight 176.00
  • Synonym(s) 4,6-Dichloro-pyridine-2-carbaldehyde
  • SMILES O=CC1=NC(Cl)=CC(Cl)=C1

Description

4,6-Dichloropicolinaldehyde delivers a highly electrophilic aldehyde group flanked by two chlorine substituents at electron-deficient positions, enabling selective coupling reactions in synthetic medicinal chemistry. This bench-stable, moisture-tolerant reagent integrates efficiently into complex molecular architectures under mild conditions.

Application

4,6-Dichloropicolinaldehyde serves as a versatile building block in heterocyclic synthesis, enabling efficient construction of bioactive scaffolds via nucleophilic addition and condensation reactions. Its electron-deficient pyridine core facilitates regioselective functionalization, while the aldehyde group offers direct access to imines, hydrazones, and other nitrogen-containing intermediates. Bench-stable and compatible with standard purification methods, it functions reliably in medicinal chemistry campaigns and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P363-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   2.2009
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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