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Structure of 3328-68-5
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5-Chloro-2-hydroxy-4-methylbenzaldehyde features a hydroxyl group ortho to the aldehyde, enabling chelation and enhanced stability, while the chloro and methyl substituents provide electronic modulation and steric control. This combination supports efficient coupling in synthetic sequences and facilitates incorporation into bioactive scaffolds under standard conditions.
5-Chloro-2-hydroxy-4-methylbenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted benzene scaffolds. The aldehyde group facilitates nucleophilic additions and condensation reactions, while the phenolic hydroxyl supports derivatization and metal-catalyzed coupling processes. Its chlorine and methyl substituents provide orthogonal reactivity handles for further functionalization. This compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for medicinal chemistry campaigns and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: