4-Bromo-5-chloro-2-fluorobenzonitrile

Name: 4-Bromo-5-chloro-2-fluorobenzonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1349716-15-9
Cat. No. CS-0334377
Purity≥96%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Bromo-5-chloro-2-fluorobenzonitrile|CS-0334377

Structure of 1349716-15-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1349716-15-9
Cat. No. CS-0334377
Purity ≥96%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₂BrClFN
Molecular Weight 234.45
Synonym(s) None
SMILES C1=C(C#N)C(=CC(=C1Cl)Br)F

Description

4-Bromo-5-chloro-2-fluorobenzonitrile features a trifunctional aromatic core with strategically positioned halogens and a nitrile group. This electron-deficient scaffold enables direct coupling in cross-coupling reactions, serving as a key building block for pharmaceutical intermediates and functional materials. The combination of bromo, chloro, and fluoro substituents provides orthogonal reactivity and enhanced metabolic stability.

Application

4-Bromo-5-chloro-2-fluorobenzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of substituted heterocycles via palladium-catalyzed cross-coupling reactions. Its orthogonal halogen reactivity profile supports sequential functionalization, while the nitrile group provides a handle for downstream transformations. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for multi-step synthetic sequences in industrial R&D workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 23.79
LogP 3.11328
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

4-Bromo-5-chloro-2-fluorobenzonitrile sigma4-Bromo-5-chloro-2-fluorobenzonitrile manufacturer4-Bromo-5-chloro-2-fluorobenzonitrile price4-Bromo-5-chloro-2-fluorobenzonitrile structure4-Bromo-5-chloro-2-fluorobenzonitrile SDSbuy 4-Bromo-5-chloro-2-fluorobenzonitrile4-Bromo-5-chloro-2-fluorobenzonitrile supplier4-Bromo-5-chloro-2-fluorobenzonitrile uses4-Bromo-5-chloro-2-fluorobenzonitrile molecular weightprice of 4-Bromo-5-chloro-2-fluorobenzonitrile4-Bromo-5-chloro-2-fluorobenzonitrile chemical name formula of 4-Bromo-5-chloro-2-fluorobenzonitrile

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Bromo-5-chloro-2-fluorobenzonitrile

CAS No. 1349716-15-9

Recommended Products