Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(4S,4'S)-2,2'-methylenebis[4,5-dihydro-4-(1-methylethyl)oxazole]

  • CAS No. 131833-90-4

  • Cat. No. CS-0086894
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4S,4'S)-2,2'-methylenebis[4,5-dihydro-4-(1-methylethyl)oxazole]|CS-0086894

Structure of 131833-90-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 131833-90-4
  • Cat. No. CS-0086894
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₂N₂O₂
  • Molecular Weight 238.33
  • Synonym(s) Bis[(S)-4-isopropyl-4,5-dihydrooxazol-2-yl]methane
  • SMILES CC(C)[C@H]1COC(CC2=N[C@@H](C(C)C)CO2)=N1

Description

This chiral bis-oxazole scaffold features a methylene bridge linking two dihydrooxazole rings, each bearing a tert-butyl substituent. The rigid, stereochemically defined structure enhances selectivity in asymmetric synthesis and serves as a robust ligand framework for transition metal catalysis under standard conditions.

Application

(4S,4'S)-2,2'-methylenebis[4,5-dihydro-4-(1-methylethyl)oxazole] serves as a chiral bis-oxazoline ligand enabling efficient asymmetric catalysis in transition-metal-mediated transformations. Its robust bench stability and defined stereochemistry facilitate reproducible enantioselective outcomes in C–C bond formation and metal-catalyzed additions. The structure supports broad functional group tolerance and simplifies purification, making it a practical choice for synthetic chemists developing stereoselective methodologies.

Synthesis

  • Route1
    • null|null
      133463-97-5
    • ~%
    • In-stock
      (4S,4'S)-2,2'-methylenebis[4,5-dihydro-4-(1-methylethyl)oxazole]|CS-0086894
      131833-90-4

    References

    • Helvetica Chimica Acta, , vol. 74, # 1 p. 232 - 240
  • Route2

    References

    • Helvetica Chimica Acta, , vol. 74, # 1 p. 232 - 240
  • Route3
    • null|null
      133463-92-0
    • ~%
    • In-stock
      (4S,4'S)-2,2'-methylenebis[4,5-dihydro-4-(1-methylethyl)oxazole]|CS-0086894
      131833-90-4

    References

    • Helvetica Chimica Acta, , vol. 74, # 1 p. 232 - 240

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   43.18
  • LogP   2.2831
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 131833-90-4 sigma131833-90-4 manufacturer131833-90-4 price131833-90-4 structure131833-90-4 SDSbuy 131833-90-4131833-90-4 supplier131833-90-4 uses131833-90-4 molecular weightprice of 131833-90-4131833-90-4 chemical name formula of 131833-90-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label