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CS-W001157 4
Total: USD 88.00

(R)-2-(4-(Tert-Butoxycarbonyl)morpholin-2-yl)acetic acid

  • CAS No. 1257848-48-8

  • Cat. No. CS-0040622
  • Purity≥95%
  • MDL No.MFCD13189486

*For research and further manufacturing use only, not for direct human use.

(R)-2-(4-(Tert-Butoxycarbonyl)morpholin-2-yl)acetic acid|CS-0040622

Structure of 1257848-48-8

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General Information

  • CAS No. 1257848-48-8
  • Cat. No. CS-0040622
  • Purity ≥95%
  • MDL No. MFCD13189486
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₅
  • Molecular Weight 245.27
  • Synonym(s) (R)-N-Boc-Morpholine-2-acetic acid
  • SMILES O=C(O)C[C@@H]1CN(C(OC(C)(C)C)=O)CCO1

Description

(R)-2-(4-(Tert-butoxycarbonyl)morpholin-2-yl)acetic acid features a chiral morpholine-bearing side chain with a protected amine, enabling direct incorporation into peptide synthesis. The tert-butyl carbamate group ensures stability during conjugation workflows and facilitates selective deprotection under mild acidic conditions. This derivative delivers precise stereochemical control in bioactive molecule construction.

Application

(R)-2-(4-(Tert-Butoxycarbonyl)morpholin-2-yl)acetic acid serves as a versatile chiral building block for the synthesis of bioactive molecules, enabling efficient access to morpholine-containing scaffolds. The tert-butyl ester group provides excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. Its well-defined stereochemistry and functional group tolerance make it ideal for peptide coupling and late-stage diversification in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   76.07
  • LogP   1.097
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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