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CS-W001157 4
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(S)-2-(4-(tert-Butoxycarbonyl)morpholin-2-yl)acetic acid

  • CAS No. 1257850-82-0

  • Cat. No. CS-0040623
  • Purity≥97%
  • MDL No.MFCD13189487

*For research and further manufacturing use only, not for direct human use.

(S)-2-(4-(tert-Butoxycarbonyl)morpholin-2-yl)acetic acid|CS-0040623

Structure of 1257850-82-0

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General Information

  • CAS No. 1257850-82-0
  • Cat. No. CS-0040623
  • Purity ≥97%
  • MDL No. MFCD13189487
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₅
  • Molecular Weight 245.27
  • Synonym(s) (S)-N-Boc-Morpholine-2-acetic acid
  • SMILES O=C(O)C[C@H]1CN(C(OC(C)(C)C)=O)CCO1

Description

(S)-2-(4-(tert-Butoxycarbonyl)morpholin-2-yl)acetic acid features a chiral morpholine scaffold with a protected amine, enabling selective conjugation in peptide synthesis. The tert-butoxycarbonyl group provides stability under standard conditions while the acetic acid moiety facilitates coupling reactions. This configuration supports efficient incorporation into bioactive sequences.

Application

(S)-2-(4-(tert-Butoxycarbonyl)morpholin-2-yl)acetic acid serves as a versatile chiral building block for peptide and small-molecule synthesis, enabling efficient access to morpholine-containing scaffolds. The protected morpholine moiety offers excellent stability and compatibility with standard coupling conditions, while the carboxylic acid group facilitates direct conjugation or further functionalization. Its defined stereochemistry ensures predictable reactivity in asymmetric synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   76.07
  • LogP   1.097
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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