2-Bromo-6-chloronicotinonitrile

Name: 2-Bromo-6-chloronicotinonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1256833-80-3
Cat. No. CS-0186588
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Bromo-6-chloronicotinonitrile|CS-0186588

Structure of 1256833-80-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1256833-80-3
Cat. No. CS-0186588
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₂BrClN₂
Molecular Weight 217.45
Synonym(s) 2-bromo-6-chloropyridine-3-carbonitrile
SMILES N#CC1=C(Br)N=C(Cl)C=C1

Description

2-Bromo-6-chloronicotinonitrile features a highly functionalized pyridine core bearing bromo, chloro, and nitrile groups at the 2-, 6-, and 3-positions, respectively. This electron-deficient heterocycle serves as a key building block in agrochemical and pharmaceutical synthesis, enabling efficient coupling reactions under standard conditions. The strategic placement of halogens facilitates selective cross-coupling transformations, while the nitrile group offers additional anchoring points for derivatization.

Application

2-Bromo-6-chloronicotinonitrile serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The nitrile group provides a handle for further functionalization, while the ortho-bromo and meta-chloro substituents offer orthogonal reactivity for sequential transformations. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis of heterocyclic scaffolds and API intermediates.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 36.68
LogP 2.36918
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

2-Bromo-6-chloronicotinonitrile sigma2-Bromo-6-chloronicotinonitrile manufacturer2-Bromo-6-chloronicotinonitrile price2-Bromo-6-chloronicotinonitrile structure2-Bromo-6-chloronicotinonitrile SDSbuy 2-Bromo-6-chloronicotinonitrile2-Bromo-6-chloronicotinonitrile supplier2-Bromo-6-chloronicotinonitrile uses2-Bromo-6-chloronicotinonitrile molecular weightprice of 2-Bromo-6-chloronicotinonitrile2-Bromo-6-chloronicotinonitrile chemical name formula of 2-Bromo-6-chloronicotinonitrile

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Bromo-6-chloronicotinonitrile

CAS No. 1256833-80-3

Recommended Products