Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(Difluoromethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

  • CAS No. 1220696-57-0

  • Cat. No. CS-0090822
  • Molecule weight255.07
  • Purity≥98%
  • MDL No.MFCD18733449

*For research and further manufacturing use only, not for direct human use.

2-(Difluoromethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine|CS-0090822

Structure of 1220696-57-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1220696-57-0
  • Cat. No. CS-0090822
  • Purity ≥98%
  • MDL No. MFCD18733449
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆BF₂NO₂
  • Molecular Weight 255.07
  • Synonym(s) None
  • SMILES CC1(C)C(C)(C)OB(C2=CN=C(C(F)F)C=C2)O1

Description

This boronate ester features a difluoromethyl group at the 2-position and a tetramethylborolane moiety at the 5-position of a pyridine core. The electron-deficient pyridine ring enables efficient cross-coupling under mild conditions, while the bench-stable boronate facilitates reliable handling and integration into diverse synthetic sequences.

Application

2-(Difluoromethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The difluoromethyl group imparts enhanced metabolic stability and modulates electronic properties, while the tetramethylboronate moiety ensures excellent bench stability, functional group tolerance, and compatibility with standard coupling conditions. This compound enables efficient construction of fluorinated heterocyclic scaffolds relevant to medicinal chemistry and agrochemical research.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   31.35
  • LogP   2.3184
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1220696-57-0 sigma1220696-57-0 manufacturer1220696-57-0 price1220696-57-0 structure1220696-57-0 SDSbuy 1220696-57-01220696-57-0 supplier1220696-57-0 uses1220696-57-0 molecular weightprice of 1220696-57-01220696-57-0 chemical name formula of 1220696-57-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label