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Structure of 1951411-51-0
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This pyridine derivative features a difluoromethyl group flanked by a boronate ester, enabling direct functionalization in cross-coupling reactions. The tetramethyl-dioxaborolane moiety ensures stability and compatibility with Suzuki-Miyaura protocols under standard conditions.
2-(Difluoromethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The difluoromethyl group imparts enhanced metabolic stability and modulates lipophilicity, making it valuable in medicinal chemistry. The pinacol boronate moiety ensures excellent bench stability, mild reaction conditions, and compatibility with diverse functional groups, enabling efficient construction of complex pyridine-based scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: