Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

tBuBrettPhos

  • CAS No. 1160861-53-9

  • Cat. No. CS-W011518
  • Purity≥97%
  • MDL No.MFCD13181930

*For research and further manufacturing use only, not for direct human use.

tBuBrettPhos|CS-W011518

Structure of 1160861-53-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1160861-53-9
  • Cat. No. CS-W011518
  • Purity ≥97%
  • MDL No. MFCD13181930
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₁H₄₉O₂P
  • Molecular Weight 484.69
  • Synonym(s) Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine; tert-ButylBrettPhos
  • SMILES COC1=CC=C(OC)C(P(C(C)(C)C)C(C)(C)C)=C1C2=C(C(C)C)C=C(C(C)C)C=C2C(C)C

Description

tBuBrettPhos is a dialkylbiaryl phosphine ligand developed by the Buchwald group. It promotes cross-coupling reactions more efficiently and exhibits improved reactivity compared to other catalytic systems.tBuBrettPhos is a phosphine ligand widely used in palladium-catalyzed cross-coupling reactions.Buchwald Phosphine Ligands for chemical Synthesis

Synthesis

  • Route1

    References

    • MASSACHUSETTS INSTITUTE OF TECHNOLOGY Patent: WO2009/76622 A2, 2009 ; Location in patent: Page/Page column 116 ;
  • Route2
    • null|null
      13716-10-4
    • In-stock
      2-Bromo-2',4',6'-triisopropyl-3,6-dimethoxy-1,1'-biphenyl|CS-0202163
      1402393-56-9
    • ~86%
    • In-stock
      tBuBrettPhos|CS-W011518
      1160861-53-9

    References

    • Hoshiya, Naoyuki; Buchwald, Stephen L. Advanced Synthesis and Catalysis, 2012 , vol. 354, # 10 p. 2031 - 2037
  • Route3
    • null|null
      13716-10-4
    • 2-Iodo-2',4',6'-triisopropyl-3,6-dimethoxy-1,1'-biphenyl|CS-0685573
      1070663-76-1
    • ~53%
    • In-stock
      tBuBrettPhos|CS-W011518
      1160861-53-9

    References

    • Fors, Brett P.; Dooleweerdt, Karin; Zeng, Qingle; Buchwald, Stephen L. Tetrahedron, 2009 , vol. 65, # 33 p. 6576 - 6583

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H317-H319-H335-H360
Precautionary Statements : P261-P264-P271-P272-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   18.46
  • LogP   9.4452
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   7

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • tBuBrettPhos sigmatBuBrettPhos manufacturertBuBrettPhos pricetBuBrettPhos structuretBuBrettPhos SDSbuy tBuBrettPhostBuBrettPhos suppliertBuBrettPhos usestBuBrettPhos molecular weightprice of tBuBrettPhostBuBrettPhos chemical name formula of tBuBrettPhos
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label