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CS-W001157 4
Total: USD 88.00

RuPhos

  • CAS No. 787618-22-8

  • Cat. No. CS-W007432
  • Purity≥97%
  • MDL No.MFCD06798294

*For research and further manufacturing use only, not for direct human use.

RuPhos|CS-W007432

Structure of 787618-22-8

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General Information

  • CAS No. 787618-22-8
  • Cat. No. CS-W007432
  • Purity ≥97%
  • MDL No. MFCD06798294
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₀H₄₃O₂P
  • Molecular Weight 466.63
  • Synonym(s) None
  • SMILES CC(C)OC1=C(C2=CC=CC=C2P(C3CCCCC3)C4CCCCC4)C(OC(C)C)=CC=C1

Description

.

Application

RuPhos serves as a highly effective, bench-stable phosphine ligand in palladium-catalyzed cross-coupling reactions, enabling efficient C–C and C–heteroatom bond formation under mild conditions. Its robustness and broad functional group tolerance facilitate reliable coupling of challenging substrates, including sterically hindered and electron-deficient partners, making it a practical choice for synthetic workflows in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      16523-54-9
    • 2'-Bromo-2,6-diisopropoxy-1,1'-biphenyl|CS-0457534
      870703-70-1
    • ~2%
    • In-stock
      RuPhos|CS-W007432
      787618-22-8

    References

    • Milne, Jacqueline E.; Buchwald, Stephen L. Journal of the American Chemical Society, 2004 , vol. 126, # 40 p. 13028 - 13032
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 126, # 40 p. 13028 - 13032
  • Route3
    • null|null
      108-46-3
    • ~%
    • In-stock
      RuPhos|CS-W007432
      787618-22-8

    References

    • Journal of the American Chemical Society, , vol. 126, # 40 p. 13028 - 13032

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332-H413
Precautionary Statements : P261-P273-P280

Quality Control

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   8.7006
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   8

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