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Structure of 1220696-57-0
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This boronate ester features a difluoromethyl group at the 2-position and a tetramethylborolane moiety at the 5-position of a pyridine core. The electron-deficient pyridine ring enables efficient cross-coupling under mild conditions, while the bench-stable boronate facilitates reliable handling and integration into diverse synthetic sequences.
2-(Difluoromethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The difluoromethyl group imparts enhanced metabolic stability and modulates electronic properties, while the tetramethylboronate moiety ensures excellent bench stability, functional group tolerance, and compatibility with standard coupling conditions. This compound enables efficient construction of fluorinated heterocyclic scaffolds relevant to medicinal chemistry and agrochemical research.
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: