2-Bromo-3-fluoro-6-(trifluoromethyl)pyridine

Name: 2-Bromo-3-fluoro-6-(trifluoromethyl)pyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1159512-38-5
Cat. No. CS-W021601
Purity≥98%
MDL No.MFCD11226611

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Bromo-3-fluoro-6-(trifluoromethyl)pyridine|CS-W021601

Structure of 1159512-38-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1159512-38-5
Cat. No. CS-W021601
Purity ≥98%
MDL No. MFCD11226611
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₂BrF₄N
Molecular Weight 243.98
Synonym(s) 2-Bromo-3-fluoro-6-(trifluoromethyl)
SMILES FC(C1=CC=C(F)C(Br)=N1)(F)F

Description

2-Bromo-3-fluoro-6-(trifluoromethyl)pyridine is a fluorinated heterocyclic building block featuring orthogonal halogen handles for selective cross-coupling. The trifluoromethyl group imparts enhanced lipophilicity and metabolic stability, while the electron-deficient pyridine core enables efficient Pd-catalyzed transformations. This compound serves as a key intermediate in medicinal chemistry and agrochemical synthesis.

Application

2-Bromo-3-fluoro-6-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the fluorine atom facilitates target engagement through polar interactions. Its bench-stable nature and compatibility with standard synthetic workflows make it ideal for constructing complex heterocyclic scaffolds and API intermediates.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 12.89
LogP 3.002
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

1159512-38-5 sigma1159512-38-5 manufacturer1159512-38-5 price1159512-38-5 structure1159512-38-5 SDSbuy 1159512-38-51159512-38-5 supplier1159512-38-5 uses1159512-38-5 molecular weightprice of 1159512-38-51159512-38-5 chemical name formula of 1159512-38-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Bromo-3-fluoro-6-(trifluoromethyl)pyridine

CAS No. 1159512-38-5

Recommended Products