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CS-W001157 4
Total: USD 88.00

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-trityl-L-lysine

  • CAS No. 111061-54-2

  • Cat. No. CS-0100972
  • Purity≥98%
  • MDL No.MFCD00270545

*For research and further manufacturing use only, not for direct human use.

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-trityl-L-lysine|CS-0100972

Structure of 111061-54-2

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General Information

  • CAS No. 111061-54-2
  • Cat. No. CS-0100972
  • Purity ≥98%
  • MDL No. MFCD00270545
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₀H₃₈N₂O₄
  • Molecular Weight 610.74
  • Synonym(s) None
  • SMILES O=C(O)[C@H](CCCCNC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)NC(OCC4C5=C(C6=C4C=CC=C6)C=CC=C5)=O

Application

N₂-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N⁶-trityl-L-lysine serves as a protected lysine building block for peptide synthesis, enabling orthogonal side-chain and α-amino protection. The Fmoc group ensures mild deprotection under basic conditions, while the trityl group provides robust protection of the ε-amino function. This dual protection strategy facilitates efficient sequential coupling in solid-phase peptide synthesis, with excellent stability, ease of purification, and compatibility with standard reaction protocols.

Synthesis

  • Route1
    • null|null
      28920-43-6
    • null|null
      111085-73-5
    • ~58%
    • In-stock
      N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-trityl-L-lysine|CS-0100972
      111061-54-2

    References

    • Barlos, Kleomenis; Mamos, Petros; Papaioannou, Dionysios; Patrianakou, Stella; Sanida, Chariklia; Schaefer, Wolfram Liebigs Annalen der Chemie, 1987 , p. 1025 - 1030
  • Route2

    References

    • Barlos, Kleomenis; Mamos, Petros; Papaioannou, Dionysios; Patrianakou, Stella; Sanida, Chariklia; Schaefer, Wolfram Liebigs Annalen der Chemie, 1987 , p. 1025 - 1030
  • Route3
    • null|null
      111061-45-1
    • ~%
    • In-stock
      N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-trityl-L-lysine|CS-0100972
      111061-54-2

    References

    • Barlos, Kleomenis; Mamos, Petros; Papaioannou, Dionysios; Patrianakou, Stella; Sanida, Chariklia; Schaefer, Wolfram Liebigs Annalen der Chemie, 1987 , p. 1025 - 1030

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   87.66
  • LogP   7.7303
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   13

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