Fmoc-D-Lys-OH.HCl

Name: Fmoc-D-Lys-OH.HCl
Brand: ChemScene
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CAS No. 201002-47-3
Cat. No. CS-W011692
Purity≥96%
MDL No.MFCD00190888

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 201002-47-3
Cat. No. CS-W011692
Purity ≥96%
MDL No. MFCD00190888
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₁H₂₅ClN₂O₄
Molecular Weight 404.89
Synonym(s) None
SMILES O=C([C@@H](CCCCN)NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)O.Cl

Description

Fmoc-D-Lys-OH·HCl is a protected amino acid derivative designed for solid-phase peptide synthesis. The Fmoc group enables orthogonal deprotection under mild basic conditions, while the D-lysine side chain offers stereochemical stability and resistance to enzymatic degradation. This variant integrates efficiently into sequences requiring non-natural D-amino acids, enhancing structural diversity in bioactive peptide design.

Application

Fmoc-D-Lys-OH·HCl serves as a key building block in solid-phase peptide synthesis, enabling the incorporation of D-lysine residues with orthogonal protection. The Fmoc group provides efficient deprotection under mild basic conditions, while the side-chain amine is selectively protected for sequential coupling. Its bench-stable crystalline form facilitates handling and purification, making it ideal for synthesizing bioactive peptides and cyclic scaffolds requiring D-amino acid incorporation.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 101.65
LogP 3.5291
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 8

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Lysine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Fmoc-D-Lys-OH.HCl

CAS No. 201002-47-3

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