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N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((4-methoxyphenyl)diphenylmethyl)-L-lysine

  • CAS No. 159857-60-0

  • Cat. No. CS-0101019
  • Purity≥95%
  • MDL No.MFCD00270542

*For research and further manufacturing use only, not for direct human use.

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((4-methoxyphenyl)diphenylmethyl)-L-lysine|CS-0101019

Structure of 159857-60-0

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General Information

  • CAS No. 159857-60-0
  • Cat. No. CS-0101019
  • Purity ≥95%
  • MDL No. MFCD00270542
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₁H₄₀N₂O₅
  • Molecular Weight 640.77
  • Synonym(s) None
  • SMILES O=C(O)[C@H](CCCCNC(C1=CC=CC=C1)(C2=CC=C(OC)C=C2)C3=CC=CC=C3)NC(OCC4C5=C(C6=C4C=CC=C6)C=CC=C5)=O

Description

This fluorenylmethoxycarbonyl-protected lysine derivative features a diphenylmethyl group at the ε-amino position, enabling selective side-chain functionalization. The 4-methoxyphenyl-diphenylmethyl moiety enhances solubility and stability during peptide synthesis. Designed for orthogonal protection strategies in solid-phase peptide assembly.

Synthesis

  • Route1

    References

    • Weinshenker, Ned M.; West, Frederick G.; Araneo, Barbara A.; Li, Weiping Patent: US2005/54607 A1, 2005 ; Location in patent: Page/Page column 17 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   96.89
  • LogP   7.7389
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   14

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