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CS-W001157 4
Total: USD 88.00

Boc-NH-PEG2-CONH-PEG2-COOH

  • CAS No. 1069067-08-8

  • Cat. No. CS-0834355
  • Purity≥98%
  • MDL No.MFCD09752854

*For research and further manufacturing use only, not for direct human use.

Boc-NH-PEG2-CONH-PEG2-COOH|CS-0834355

Structure of 1069067-08-8

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General Information

  • CAS No. 1069067-08-8
  • Cat. No. CS-0834355
  • Purity ≥98%
  • MDL No. MFCD09752854
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₃₂N₂O₉
  • Molecular Weight 408.45
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCOCCOCC(=O)NCCOCCOCC(=O)O

Description

This macrocyclic diacid features a rigid, electron-deficient framework with five ether linkages and two terminal carboxylic acid groups. Designed for high-affinity metal ion chelation, the structure integrates sterically protected binding pockets that enhance selectivity in complex aqueous environments.

Application

2,2-Dimethyl-4,13-dioxo-3,8,11,17,20-pentaoxa-5,14-diazadocosan-22-oic acid serves as a versatile bifunctional building block for macrocyclic and peptidomimetic synthesis. Its terminal carboxylic acid enables conjugation via standard amide coupling, while the pendant amine facilitates orthogonal functionalization. The polyether backbone provides solubility and conformational rigidity, supporting applications in targeted delivery systems and high-throughput screening libraries. Bench-stable and readily purified by precipitation or chromatography, it functions effectively in both solution-phase and solid-phase workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   141.65
  • LogP   -0.2217
  • H_Acceptors   8
  • H_Donors   3
  • Rotatable_Bonds   16

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