2-Bromo-4-cyclopropylpyridine

Name: 2-Bromo-4-cyclopropylpyridine
Brand: ChemScene
Availability: OutOfStock
Rating: 5 (1 reviews)

CAS No. 1086381-39-6
Cat. No. CS-0321368
Molecule weight198.06
Purity95+%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Bromo-4-cyclopropylpyridine|CS-0321368

Structure of 1086381-39-6

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1086381-39-6
Cat. No. CS-0321368
Purity 95+%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈BrN
Molecular Weight 198.06
Synonym(s) None
SMILES BrC1=NC=CC(C2CC2)=C1

Description

2-Bromo-4-cyclopropylpyridine features a cyclopropyl group at the 4-position and a bromine atom at the 2-position of the pyridine ring, creating a sterically constrained, electron-deficient heteroaromatic scaffold. This configuration enables selective coupling reactions in medicinal chemistry, particularly in Suzuki-Miyaura and Buchwald-Hartwig transformations, where its stability under catalytic conditions supports efficient construction of complex nitrogen-containing architectures.

Application

2-Bromo-4-cyclopropylpyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions to construct biaryl and heteroaryl scaffolds. The bromine moiety facilitates efficient functionalization under standard Suzuki, Stille, or Negishi conditions, while the cyclopropyl group imparts favorable lipophilic character and metabolic stability. Bench-stable and readily purified by column chromatography, it functions reliably in multi-step synthesis of kinase inhibitors and other pharmaceutical intermediates.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 12.89
LogP 2.7215
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Fatty ring compounds Cyclopropane compounds

Key Words

2-Bromo-4-cyclopropylpyridine sigma2-Bromo-4-cyclopropylpyridine manufacturer2-Bromo-4-cyclopropylpyridine price2-Bromo-4-cyclopropylpyridine structure2-Bromo-4-cyclopropylpyridine SDSbuy 2-Bromo-4-cyclopropylpyridine2-Bromo-4-cyclopropylpyridine supplier2-Bromo-4-cyclopropylpyridine uses2-Bromo-4-cyclopropylpyridine molecular weightprice of 2-Bromo-4-cyclopropylpyridine2-Bromo-4-cyclopropylpyridine chemical name formula of 2-Bromo-4-cyclopropylpyridine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Bromo-4-cyclopropylpyridine

CAS No. 1086381-39-6

Recommended Products