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Structure of 579475-29-9
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5-Bromo-2-cyclopropylpyridine features a cyclopropyl group at the 2-position and a bromine atom at the 5-position of the pyridine ring, creating a sterically constrained, electron-deficient heteroaryl scaffold. This configuration enables direct coupling in palladium-catalyzed cross-coupling reactions, delivering complex substituted pyridines with high regiocontrol. The molecule exhibits excellent bench stability and compatibility with standard reaction conditions.
5-Bromo-2-cyclopropylpyridine serves as a versatile building block in medicinal chemistry and catalytic cross-coupling reactions. The bromine substituent enables reliable Suzuki, Stille, and Negishi couplings, while the cyclopropyl group imparts metabolic stability and modulates electronic properties. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: