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Structure of 99455-05-7
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6-Bromo-2-methoxyquinoline is a halogenated quinoline derivative featuring a bromine atom at the 6-position and a methoxy group at the 2-position. This electron-deficient scaffold enables direct coupling in palladium-catalyzed cross-coupling reactions, serving as a key building block in pharmaceutical synthesis and materials chemistry.
6-Bromo-2-methoxyquinoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromine functionality. The 2-methoxy group enhances solubility and modulates electronic properties, while the quinoline core provides a rigid, planar scaffold suitable for drug discovery applications. Bench-stable and readily purified by flash chromatography, it functions reliably in standard synthetic workflows involving Suzuki, Stille, or Negishi coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: