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CS-W001157 4
Total: USD 88.00

7-Bromo-2-methoxyquinoline

  • CAS No. 99455-08-0

  • Cat. No. CS-W022528
  • Molecule weight238.08
  • Purity≥98%
  • MDL No.MFCD11877930

*For research and further manufacturing use only, not for direct human use.

7-Bromo-2-methoxyquinoline|CS-W022528

Structure of 99455-08-0

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General Information

  • CAS No. 99455-08-0
  • Cat. No. CS-W022528
  • Purity ≥98%
  • MDL No. MFCD11877930
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BrNO
  • Molecular Weight 238.08
  • Synonym(s) None
  • SMILES COC1=NC2=CC(Br)=CC=C2C=C1

Description

7-Bromo-2-methoxyquinoline is a halogenated quinoline derivative featuring a bromine atom at the 7-position and a methoxy group at the 2-position. This electron-deficient scaffold integrates readily into transition metal-catalyzed cross-coupling reactions, enabling efficient construction of complex heterocyclic architectures in medicinal chemistry and materials science applications.

Application

7-Bromo-2-methoxyquinoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromine functionality. The 2-methoxy group enhances solubility and modulates electronic properties, while the quinoline core provides structural rigidity for targeted scaffold development. This compound exhibits excellent bench stability and facilitates straightforward purification, making it suitable for iterative synthesis workflows in API discovery and process chemistry applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   3.0059
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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