Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Bromo-5-chloropyrazolo[1,5-a]pyrimidine

  • CAS No. 960613-96-1

  • Cat. No. CS-W019638
  • Purity≥98%
  • MDL No.MFCD11520857

*For research and further manufacturing use only, not for direct human use.

3-Bromo-5-chloropyrazolo[1,5-a]pyrimidine|CS-W019638

Structure of 960613-96-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 960613-96-1
  • Cat. No. CS-W019638
  • Purity ≥98%
  • MDL No. MFCD11520857
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrClN₃
  • Molecular Weight 232.47
  • Synonym(s) 3-bromo-5-chloro-pyrazolo[1,5-a]pyrimidine
  • SMILES ClC1=NC2=C(Br)C=NN2C=C1

Description

3-Bromo-5-chloropyrazolo[1,5-a]pyrimidine features a fused heterocyclic core with orthogonal halogen substituents enabling selective functionalization. This electron-deficient scaffold integrates readily into cross-coupling cascades and serves as a key intermediate in the synthesis of bioactive pyrazolopyrimidine derivatives.

Application

3-Bromo-5-chloropyrazolo[1,5-a]pyrimidine serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its dual halogenation pattern enables sequential cross-coupling reactions, facilitating the construction of complex pyrazolo[1,5-a]pyrimidine scaffolds. The compound exhibits excellent bench stability and compatibility with palladium-catalyzed coupling protocols, supporting efficient functionalization under standard reaction conditions.

Synthesis

  • Route1

    References

    • BAYER SCHERING PHARMA AKTIENGESELLSCHAFT Patent: WO2007/147647 A1, 2007 ; Location in patent: Page/Page column 60 ;
  • Route2

    References

    • WO2011/29027 A1, ; WO 2011/029027 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   30.19
  • LogP   2.1452
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 960613-96-1 sigma960613-96-1 manufacturer960613-96-1 price960613-96-1 structure960613-96-1 SDSbuy 960613-96-1960613-96-1 supplier960613-96-1 uses960613-96-1 molecular weightprice of 960613-96-1960613-96-1 chemical name formula of 960613-96-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label