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CS-W001157 4
Total: USD 88.00

5,6-Dichloro-1H-benzo[d]imidazole

  • CAS No. 6478-73-5

  • Cat. No. CS-W022274
  • Purity≥98%
  • MDL No.MFCD00211325

*For research and further manufacturing use only, not for direct human use.

5,6-Dichloro-1H-benzo[d]imidazole|CS-W022274

Structure of 6478-73-5

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General Information

  • CAS No. 6478-73-5
  • Cat. No. CS-W022274
  • Purity ≥98%
  • MDL No. MFCD00211325
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄Cl₂N₂
  • Molecular Weight 187.03
  • Synonym(s) 5,6-Dichloro-1H-benzimidazole
  • SMILES ClC1=C(Cl)C=C2C(NC=N2)=C1

Description

5,6-Dichloro-1H-benzo[d]imidazole features two chlorine atoms at the 5 and 6 positions of the imidazole ring, enhancing electron deficiency and stability. This configuration supports its use in heterocyclic synthesis, particularly as a building block for pharmaceutical intermediates and functional materials requiring halogenated aromatic scaffolds.

Synthesis

  • Route1
    • In-stock
      1,2-Diamino-4,5-dichlorobenzene|CS-D1350
      5348-42-5
    • null|null
      64-18-6
    • ~95%
    • In-stock
      5,6-Dichloro-1H-benzo[d]imidazole|CS-W022274
      6478-73-5

    References

    • Wu, Wen-Lian; Burnett, Duane A.; Caplen, Mary Ann; Domalski, Martin S.; Bennett, Chad; Greenlee, William J.; Hawes, Brian E.; O'Neill, Kim; Weig, Blair; Weston, Daniel; Spar, Brian; Kowalski, Timothy Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 14 p. 3674 - 3678
  • Route2
    • In-stock
      1,2-Diamino-4,5-dichlorobenzene|CS-D1350
      5348-42-5
    • null|null
      64-18-6
    • null|null
      149-73-5
    • ~75%
    • In-stock
      5,6-Dichloro-1H-benzo[d]imidazole|CS-W022274
      6478-73-5

    References

    • Kuntz, Kevin; Emmitte, Kyle Allen; Rheault, Tara Renae; Smith, Stephon; Hornberger, Keith; Dickson, Hamilton; Cheung, Mui Patent: US2008/300247 A1, 2008 ; Location in patent: Page/Page column 107 ;
  • Route3
    • null|null
      122-51-0
    • In-stock
      4,5-Dichloro-2-nitroaniline|CS-W015295
      6641-64-1
    • ~93%
    • In-stock
      5,6-Dichloro-1H-benzo[d]imidazole|CS-W022274
      6478-73-5

    References

    • Wang, Fen; Tran-Dube, Michelle; Scales, Stephanie; Johnson, Sarah; McAlpine, Indrawan; Ninkovic, Sacha Tetrahedron Letters, 2013 , vol. 54, # 31 p. 4054 - 4057

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.8697
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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