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CS-W001157 4
Total: USD 88.00

3-Bromopyrazolo[1,5-a]pyrimidine

  • CAS No. 55405-67-9

  • Cat. No. CS-W009241
  • Purity≥98%
  • MDL No.MFCD09832893

*For research and further manufacturing use only, not for direct human use.

3-Bromopyrazolo[1,5-a]pyrimidine|CS-W009241

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General Information

  • CAS No. 55405-67-9
  • Cat. No. CS-W009241
  • Purity ≥98%
  • MDL No. MFCD09832893
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄BrN₃
  • Molecular Weight 198.02
  • Synonym(s) 3-BROMO-PYRAZOLO[1,5-A]PYRIMIDINE
  • SMILES BrC1=C2N=CC=CN2N=C1

Description

3-Bromopyrazolo[1,5-a]pyrimidine serves as a pivotal heterocyclic scaffold for medicinal chemistry and materials science. This brominated pyrazolopyrimidine integrates readily into diverse synthetic pathways, offering a reactive handle for cross-coupling reactions. The molecule exhibits enhanced stability under standard conditions, enabling efficient incorporation into complex molecular architectures.

Application

3-Bromopyrazolo[1,5-a]pyrimidine serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its bromine substituent enables facile palladium-catalyzed cross-coupling reactions, including Suzuki, Stille, and Buchwald-Hartwig transformations. The pyrazolo[1,5-a]pyrimidine core exhibits good bench stability and compatibility with diverse functional groups, facilitating efficient access to complex scaffolds in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   30.19
  • LogP   1.4918
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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