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CS-W001157 4
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(S)-Tetrahydro-1H-oxazolo[3,4-a]pyrazin-3(5H)-one hydrochloride

  • CAS No. 958635-15-9

  • Cat. No. CS-W001850
  • Purity≥97%
  • MDL No.MFCD09878826

*For research and further manufacturing use only, not for direct human use.

(S)-Tetrahydro-1H-oxazolo[3,4-a]pyrazin-3(5H)-one hydrochloride|CS-W001850

Structure of 958635-15-9

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General Information

  • CAS No. 958635-15-9
  • Cat. No. CS-W001850
  • Purity ≥97%
  • MDL No. MFCD09878826
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁ClN₂O₂
  • Molecular Weight 178.62
  • Synonym(s) (S)-Tetrahydro-1H-oxazolo[3,4-a]pyrazin-3(5H)-one hydrochloride
  • SMILES O=C1OC[C@H]2N1CCNC2.Cl

Description

This bicyclic heterocycle features a rigid, saturated oxazolopiperazinone core with enhanced solubility and stability in aqueous media. The hydrochloride salt form ensures excellent crystallinity and ease of handling, enabling straightforward incorporation into peptide-based scaffolds and medicinal chemistry campaigns.

Application

(8aS)-Hexahydro-1H-[1,3]oxazolo[3,4-a]piperazin-3-one hydrochloride serves as a stable, bench-ready heterocyclic building block for medicinal chemistry applications. Its rigid fused oxazolopiperazinone core enables efficient access to diverse nitrogen-containing scaffolds, particularly in CNS-targeted compound libraries. The hydrochloride salt enhances solubility and handling, while the functional group tolerance supports straightforward derivatization via nucleophilic substitution or reductive amination. Functions reliably in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   -0.1678
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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