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CS-W001157 4
Total: USD 88.00

3-(4-Methoxyphenyl)pyrrolidine

  • CAS No. 91246-26-3

  • Cat. No. CS-0150400
  • Purity≥97%
  • MDL No.MFCD09027609

*For research and further manufacturing use only, not for direct human use.

3-(4-Methoxyphenyl)pyrrolidine|CS-0150400

Structure of 91246-26-3

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General Information

  • CAS No. 91246-26-3
  • Cat. No. CS-0150400
  • Purity ≥97%
  • MDL No. MFCD09027609
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₅NO
  • Molecular Weight 177.24
  • Synonym(s) None
  • SMILES COC1=CC=C(C=C1)C2CCNC2

Description

3-(4-Methoxyphenyl)pyrrolidine features a pyrrolidine ring linked to a para-methoxyphenyl group, delivering enhanced solubility and metabolic stability. This electron-rich scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for targeted ligand design.

Application

3-(4-Methoxyphenyl)pyrrolidine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive compounds through its stable pyrrolidine core and ortho-substituted aryl functionality. The methoxy group enhances solubility and modulates electronic properties, while the secondary amine facilitates conjugation in standard coupling reactions. This compound exhibits excellent bench stability and is compatible with common protecting group strategies, making it ideal for iterative synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   1.7721
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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