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CS-W001157 4
Total: USD 88.00

(2-Formyl-3-methoxyphenyl)boronic acid

  • CAS No. 958030-46-1

  • Cat. No. CS-0174138
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-Formyl-3-methoxyphenyl)boronic acid|CS-0174138

Structure of 958030-46-1

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General Information

  • CAS No. 958030-46-1
  • Cat. No. CS-0174138
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BO₄
  • Molecular Weight 179.97
  • Synonym(s) (3-methoxy-2-formyl-phenyl)boronic acid
  • SMILES COC1=CC=CC(B(O)O)=C1C=O

Description

This boronic acid features a formyl group ortho to the boronate, enabling direct coupling in Suzuki-Miyaura reactions. The methoxy substituent enhances solubility and stabilizes the boronate under standard conditions. Designed for efficient integration into complex molecular architectures.

Application

(2-Formyl-3-methoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling the efficient construction of biaryl scaffolds under mild conditions. The ortho-formyl group provides a handle for downstream functionalization via condensation or oxidation reactions, while the methoxy substituent enhances solubility and modulates electronic properties. Bench-stable and compatible with a range of reaction conditions, it facilitates the synthesis of complex heterocycles and functionalized aromatic systems relevant to medicinal chemistry and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   66.76
  • LogP   -0.8125
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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