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CS-W001157 4
Total: USD 88.00

(4-Formyl-3-methoxyphenyl)boronic acid

  • CAS No. 815620-00-9

  • Cat. No. CS-0132530
  • Purity≥98%
  • MDL No.MFCD10697427

*For research and further manufacturing use only, not for direct human use.

(4-Formyl-3-methoxyphenyl)boronic acid|CS-0132530

Structure of 815620-00-9

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General Information

  • CAS No. 815620-00-9
  • Cat. No. CS-0132530
  • Purity ≥98%
  • MDL No. MFCD10697427
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BO₄
  • Molecular Weight 179.97
  • Synonym(s) None
  • SMILES OB(C1=CC=C(C=O)C(OC)=C1)O

Description

This boronic acid features a formyl group ortho to the boronate, enabling direct coupling in Suzuki-Miyaura reactions without prior derivatization. The methoxy substituent enhances solubility and stabilizes the boronate under standard conditions.

Application

(4-Formyl-3-methoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The ortho-methoxy and formyl groups provide complementary sites for downstream functionalization, while the boronic acid moiety offers excellent bench stability and ease of purification. Its compatibility with diverse reaction partners makes it a practical choice for synthesizing complex aromatic architectures in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P261-P280-P304+P340-P405

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Computational Chemistry Data

  • TPSA   66.76
  • LogP   -0.8125
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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