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CS-W001157 4
Total: USD 88.00

(4-Formyl-3,5-dimethoxyphenyl)boronic acid

  • CAS No. 2001080-85-7

  • Cat. No. CS-0135512
  • Purity≥96%
  • MDL No.MFCD22383667

*For research and further manufacturing use only, not for direct human use.

(4-Formyl-3,5-dimethoxyphenyl)boronic acid|CS-0135512

Structure of 2001080-85-7

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General Information

  • CAS No. 2001080-85-7
  • Cat. No. CS-0135512
  • Purity ≥96%
  • MDL No. MFCD22383667
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BO₅
  • Molecular Weight 209.99
  • Synonym(s) 4-ForMyl-3,5-diMethoxyphenylboronic acid
  • SMILES OB(C1=CC(OC)=C(C=O)C(OC)=C1)O

Description

This boronic acid features a formyl group flanked by two methoxy substituents on the aromatic ring, enabling direct functionalization in Suzuki-Miyaura couplings. The electron-rich aryl framework enhances reactivity while maintaining bench-stable handling characteristics under standard conditions.

Application

(4-Formyl-3,5-dimethoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The ortho-dimethoxy substitution enhances stability and solubility, while the formyl group provides a handle for downstream functionalization via condensation or reductive amination. Bench-stable and compatible with diverse reaction partners, it facilitates rapid access to complex phenolic architectures relevant to medicinal chemistry and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.99
  • LogP   -0.8039
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   4

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