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Structure of 955369-43-4
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This boronate moiety features a sterically hindered hydroxyl group adjacent to the phenyl ring, enhancing stability and solubility in aqueous-organic mixtures. The para-hydroxyisopropyl substitution pattern enables efficient Suzuki-Miyaura coupling under mild conditions, delivering high-yielding biaryl architectures with minimal protodeboronation.
(3-(2-Hydroxypropan-2-yl)phenyl)boronic acid serves as a stable, bench-ready arylboronic acid for Suzuki-Miyaura coupling reactions. Its tertiary alcohol group enhances solubility and minimizes protodeboronation, enabling reliable cross-coupling with aryl halides and triflates under standard conditions. The compound functions as a key building block for biaryl scaffolds in medicinal chemistry and materials science, offering predictable reactivity and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: