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CS-W001157 4
Total: USD 88.00

Boronic acid, B-[3-(1-hydroxy-1-methylethyl)phenyl]-

  • CAS No. 955369-43-4

  • Cat. No. CS-0029532
  • Purity≥97%
  • MDL No.MFCD09992906
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Boronic acid, B-[3-(1-hydroxy-1-methylethyl)phenyl]-|CS-0029532

Structure of 955369-43-4

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Description

This boronate moiety features a sterically hindered hydroxyl group adjacent to the phenyl ring, enhancing stability and solubility in aqueous-organic mixtures. The para-hydroxyisopropyl substitution pattern enables efficient Suzuki-Miyaura coupling under mild conditions, delivering high-yielding biaryl architectures with minimal protodeboronation.

Application

(3-(2-Hydroxypropan-2-yl)phenyl)boronic acid serves as a stable, bench-ready arylboronic acid for Suzuki-Miyaura coupling reactions. Its tertiary alcohol group enhances solubility and minimizes protodeboronation, enabling reliable cross-coupling with aryl halides and triflates under standard conditions. The compound functions as a key building block for biaryl scaffolds in medicinal chemistry and materials science, offering predictable reactivity and straightforward purification.

General Information

  • CAS No. 955369-43-4
  • Cat. No. CS-0029532
  • Purity ≥97%
  • MDL No. MFCD09992906
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃BO₃
  • Molecular Weight 180.01
  • Synonym(s) 3-(2-hydroxypropan-2-yl)phenylboronic acid
  • SMILES CC(C1=CC(B(O)O)=CC=C1)(O)C

Computational Chemistry Data

  • TPSA   60.69
  • LogP   -0.4062
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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