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Structure of 1202054-12-3
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This trifluoromethyl-substituted pyrazole boronic acid integrates a robust, electron-deficient heterocyclic scaffold with a reactive boronate handle. The para-trifluoromethyl group enhances metabolic stability and modulates electronic properties, enabling efficient Suzuki-Miyaura coupling under standard conditions. Designed for streamlined access to bioactive arylated heterocycles in medicinal chemistry and materials science applications.
(3-(Trifluoromethyl)-1H-pyrazol-4-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, making it valuable for constructing bioactive heterocycles. The boronic acid functionality offers excellent bench stability, straightforward purification, and broad functional group tolerance, facilitating its use in medicinal chemistry and process-scale synthesis.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: