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Boronic acid, B-[3-(1-hydroxyethyl)phenyl]-

  • CAS No. 1036760-03-8

  • Cat. No. CS-0029537
  • Purity≥98%
  • MDL No.MFCD04112541

*For research and further manufacturing use only, not for direct human use.

Boronic acid, B-[3-(1-hydroxyethyl)phenyl]-|CS-0029537

Structure of 1036760-03-8

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General Information

  • CAS No. 1036760-03-8
  • Cat. No. CS-0029537
  • Purity ≥98%
  • MDL No. MFCD04112541
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BO₃
  • Molecular Weight 165.98
  • Synonym(s) [3-(1-hydroxyethyl)phenyl]boronic acid
  • SMILES CC(C1=CC(B(O)O)=CC=C1)O

Description

This boronate moiety integrates a phenyl ring bearing a para-hydroxyethyl substituent, delivering enhanced solubility and stability under standard conditions. The hydroxyl group facilitates hydrogen bonding and improves aqueous compatibility, while the boronic acid functionality enables efficient Suzuki-Miyaura cross-coupling reactions.

Application

(3-(1-Hydroxyethyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The pendant hydroxyl group enhances solubility and facilitates purification, while the boronic acid moiety exhibits robust stability during storage and compatibility with diverse functional groups. Its structure supports the synthesis of substituted biaryls and complex heterocycles relevant to medicinal chemistry and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   60.69
  • LogP   -0.5803
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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