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CS-W001157 4
Total: USD 88.00

2,8-Diazaspiro[4.5]decan-3-one hydrochloride

  • CAS No. 945892-88-6

  • Cat. No. CS-W020525
  • Purity≥97%
  • MDL No.MFCD11520496

*For research and further manufacturing use only, not for direct human use.

2,8-Diazaspiro[4.5]decan-3-one hydrochloride|CS-W020525

Structure of 945892-88-6

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General Information

  • CAS No. 945892-88-6
  • Cat. No. CS-W020525
  • Purity ≥97%
  • MDL No. MFCD11520496
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅ClN₂O
  • Molecular Weight 190.67
  • Synonym(s) None
  • SMILES O=C(C1)NCC21CCNCC2.Cl

Description

This spirocyclic ketone features a rigid, electron-deficient core with dual nitrogen atoms positioned at the 2 and 8 ring junctions, enhancing its utility in medicinal chemistry. The hydrochloride salt improves solubility and stability for use in synthetic transformations and target-directed library synthesis under standard conditions.

Application

2,8-Diazaspiro[4.5]decan-3-one hydrochloride serves as a stable, crystalline scaffold for the synthesis of biologically relevant heterocycles. Its rigid spirocyclic framework with orthogonal nitrogen functionalities enables selective functionalization and facilitates transition metal-catalyzed coupling reactions. The hydrochloride salt enhances solubility and handling in aqueous and polar organic media, supporting efficient purification and reproducible reaction outcomes in medicinal chemistry workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   41.13
  • LogP   0.2979
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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