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Structure of 799274-08-1
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6-Fluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride features a fluorinated tetrahydroisoquinoline core with enhanced metabolic stability and improved membrane permeability. This bench-stable salt form facilitates handling in synthetic workflows, enabling efficient incorporation into bioactive molecules for medicinal chemistry applications.
6-Fluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride serves as a valuable building block in medicinal chemistry, enabling efficient access to bioactive isoquinoline scaffolds. Its fluorinated aromatic core enhances metabolic stability and modulates electronic properties, while the protonated amine facilitates salt formation for improved solubility and handling. The compound exhibits robust functional group tolerance and participates reliably in standard coupling reactions, making it well-suited for the synthesis of CNS-targeted therapeutics and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: