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Structure of 799274-06-9
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7-Fluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride is a bench-stable, moisture-tolerant heterocyclic amine featuring a fluorinated aromatic ring fused to a saturated nitrogen-containing backbone. This structure integrates a potent electron-withdrawing fluorine at the 7-position, enhancing metabolic stability and modulating basicity for improved solubility in aqueous media. The hydrochloride salt form ensures high purity and ease of handling, enabling direct use in synthetic transformations, medicinal chemistry campaigns, and drug discovery workflows where precise electronic tuning is required.
7-Fluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride serves as a valuable building block in medicinal chemistry, enabling efficient access to bioactive isoquinoline scaffolds. Its fluorinated aromatic system enhances metabolic stability and modulates electronic properties, while the protonated nitrogen facilitates salt formation for improved solubility and handling. The compound exhibits excellent functional group tolerance and reactivity in standard coupling and alkylation reactions, making it ideal for iterative synthesis of CNS-targeted candidates and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: